Aspirin for Heart Health & LPA Genetic Test - Gene Food

Aspirin + Gene Food Diet Type

$424Kit plus Health Intelligence. One-time price.
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Included with Health Intelligence

Learn your status for genes associated with elevated Lp(a) with the Gene Food lipoprotein (a) genetic test and the Aspirin & Heart Health report.

  • CLIA-Certified Lab
  • Personalized DNA insights
  • Data Never Sold

What You'll Learn

  • Tests for rs3798220 in the LPA gene
  • Data is 100% confidential and secure
  • Personalized nutrition recommendations
  • Learn your Gene Food diet type
Aspirin & heart health report

Learn whether you carry genetic markers associated with elevated Lp(a)

Baby aspirin is no longer recommended to the general public to prevent heart attack and stroke.

However, carriers of the "C" allele for rs3798220 in the LPA gene, which often means elevated Lp(a) levels, could benefit from Aspirin to reduce the risk heart of cardiac events, according to the ASPREE Trial and Women’s Health Study. It is important to note that the applicability of the findings is limited to individuals of European descent. The Gene Food Aspirin & Heart Health report tests for rs3798220 in the LPA gene so customers can discuss the results with their physician.

Explore Plans
Aspirin & heart health report example
Illustrative report example, not your personal results.
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The best DNA diet app
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“I’ve tried several other companies, including InsiderTracker and DNAfit; if your primary concern is diet then I would absolutely recommend Gene Food as the best of the bunch.”

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Carbs are GOOD
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“Once I went back to carbs (based on the Okinawa diet) and quit the whole 30/paleo diet as well as any attempts at Keto or low-carb, my weight stopped rising, and actually started to go down (and I didn’t even follow the Okinawa diet very strictly, and did no caloric restriction)!”

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Okinawan
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Diet Types

Twenty unique diet types, where will you fit?

Gene Food uses a proprietary algorithm to divide customers into one of twenty unique diet types based on dietary fat metabolism, ApoE status, carbohydrate response, histamine, and ability to digest lactose. Where will you fit?

West Angeleno

Healthy fats from whole foods, whole grains, fresh over leftovers, and two plant-based days a week.

Low carb, high fat

Wayoan

Plant-based and low-fat. Meat as a condiment, most dairy out, calories from complex carbs, wild fish for protein.

Macrobiotic template

Lean Machine

Whole grains and plant fats, no dairy, protein mostly from plants with wild fish to hold muscle.

Whole grains, plant fats

Villager

Low-fat, whole-food and plant-based. No oil, fresh over aged foods, calories from complex carbohydrates.

Low glycemic, low fat

Okinawan

Fiber-rich complex carbs make up most calories; saturated fat kept low, no seed oils, animal protein as a condiment.

High carb, very low fat

Vegetarian

Plants first with fish in the rotation. Complex carbs for calories, olive oil only, fresh foods to keep histamine down.

High carb, low fat

Urban Grazer

Robust genes, few restrictions. Whole grains, healthy fats, plant proteins, no dairy or processed meat.

Balanced, few limits

Hunter Gatherer

Omega-3s over saturated fat, low-glycemic carbs, mostly plant protein, and fresh foods to keep histamine in check.

Low glycemic, higher protein

Find your diet type
Purchase GeneFood

Find out how your body actually handles carbs

Low-carb works for some people and backfires for others. In the PREDICT-1 trial, genetics accounted for nearly half of the variation in how much blood sugar rose two hours after a meal. Our CLIA-certified test scores your carbohydrate response across multiple validated SNPs, matches you to one of 20 diet types, and turns it into a plan: the carbs that suit you, the ones to limit, and a two-week meal plan built around them.

Gene Food DNA test collection kit

Frequently asked questions

Both the ASPREE Trial and Women's Health Study (WHS) indicate that low-dose aspirin might be advantageous for individuals carrying the C-allele of rs3798220 (LPA gene) in individuals with no previous history of heart disease.

The median Lp(a) levels in individuals carrying one copy of the minor allele C for rs3798220 (heterozygous) were eight times higher while those carrying two copies (homozygous) were 15 times higher compared to individuals who didn’t have the C allele.

  • C/C: 153.9 mg/dL in 15 individuals
  • T/C: 79.5 mg/dL in 906 individuals
  • T/T: 10.0 mg/dL in 24204 individuals

We did a full write-up summarizing ASPREE and the WHS findings as they relate to Lp(a), here.

To summarize:

  • ASPREE - In the group of people who received a fake treatment (the placebo group), having the rs3798220-C allele made them almost twice as likely to have heart problem (MACE) compared to those without the gene (HR (Hazard’s ratio): 1.90). However, in the group that took Aspirin, the risk of heart problems (MACE) for those with the rs3798220-C allele wasn’t significantly different from those without it (HR: 0.54).
  • WHS - In the group of women who received a fake treatment (the placebo group), women who had one or more copies of the rs3798220-C allele had a roughly 2-fold greater risk of experiencing major cardiovascular events compared to those who didn’t have this allele (HR:2.2). For women with the rs3798220-C allele, taking aspirin instead of a placebo reduced their risk of major heart problems by 56%, which means they were less likely to have these issues (HR:0.44). On the other hand, for those without the rs3798220-C allele, aspirin didn’t show a significant reduction in the risk of major heart problems (HR:0.91).

Lp(a) has been shown to increase the risk of blood clots, which could explain the benefit of aspirin in groups carrying the C allele for rs3798220.

Only modestly. The primary driver of Lp(a) levels is genetics.

This report is available with the Methylation Bundle (Health Intelligence), alongside the core reports included with your Gene Food DNA test. Current bundle pricing is shown above.

Like all our tests, the Aspirin & Heart Health report is a simple cheek swab test. A self-addressed return envelope is included with the test kit, as are detailed instructions for taking the test. The swab sample is sent to our CLIA-certified laboratory in Houston, where the sequencing occurs.