Caffeine + Gene Food Diet Type

GeneFood test collection kit on a wooden table

Open GeneFood test kit on a wooden table, showing two labeled sample tubes in the box, the instruction manual, and two sealed cheek swabs

Example result: diet type California Keto, with supplement findings

Your diet type

California Keto

Farmer's markets and fat.

Fat 40% · Protein 20% · Carbs 40%

Your supplement findings

MagnesiumHigher needs likely

ZincLower status likely

CholineIncreased requirement

One of 20 types. Decided by your genes, not a quiz. Plus a 14-day meal plan built around it.

Example results. Gene Food provides nutrition and wellness information, not medical advice.

Included in Methylation Bundle. Get the methylation answers you have been looking for. The Gene Food methylation report shown on a phone: a Reduced MTHFR activity status, MTHFR C677T CT, MTHFR A1298C AA and COMT Val158Met AG, and a plain-English summary.

Customer quote: Acquiring a custom nutrition plan from Gene Food was the single best health decision of my adult life.

Gerald lowered his LDL cholesterol by 100 points by changing his diet. LDL 192 to 88 mg/dL, ApoB 152 to 73 mg/dL, blood pressure 150/80 to 111/65.

$229One-time price. No subscription.

Included with Basic

Genetics plays a big role in how people respond to caffeine. Learn your status for the CYP1A2 gene, the key genetic marker involved in caffeine metabolism.

CLIA-Certified Lab
Personalized DNA insights
Data Never Sold

What You'll Learn

Tests for CYP1A2 variants linked to slow and fast caffeine metabolism
Data is 100% confidential and secure
Personalized nutrition recommendations
Learn your Gene Food diet type

Caffeine metabolism report

Learn how fast your body metabolizes caffeine

Caffeine is the world’s most popular drug, but how people metabolize caffeine varies based on genetics. The Gene Food caffeine metabolism report looks at the genes that drive differences in caffeine metabolism, specifically CYP1A2 rs762551. A/C and C/C genotypes may want to avoid caffeine, especially in large doses, as their bodies metabolize it more slowly than A/A genotypes. While not all studies are in agreement, there is some evidence in the literature that slow metabolizers increase their heart attack risk when they consume large amounts of caffeine, and this is true even for younger individuals.

Explore Plans

Caffeine metabolism report example — Illustrative report example, not your personal results.

Reviews

Satisfied customers

Amazing

★★★★★

“Gene Food completely changed the way I approach nutrition. Meal plan is easy to follow, results were ready in 15 minutes, and I no longer crave sweets.”

Jamila Lynn

Hunter Gatherer

The best DNA diet app

★★★★★

“I’ve tried several other companies, including InsiderTracker and DNAfit; if your primary concern is diet then I would absolutely recommend Gene Food as the best of the bunch.”

Alexis Philippou

Urban Grazer

Carbs are GOOD

★★★★★

“Once I went back to carbs (based on the Okinawa diet) and quit the whole 30/paleo diet as well as any attempts at Keto or low-carb, my weight stopped rising, and actually started to go down (and I didn’t even follow the Okinawa diet very strictly, and did no caloric restriction)!”

Kat C.

Okinawan

Best health decision of my adult life

★★★★★

“Acquiring a custom nutrition plan from Gene Food was the single best health decision of my adult life. I frequent the Gene Food blog & the Gene Food podcast. John O’Connor and Dr. Aaron Gardner are focused on providing individuals with the very best science based information today. I believe their individualized approach, not the “one size fits all” seen frequently, is the future of optimizing health and wellness.”

Bethny Brown-Avila

Wayoan

Diet Types

Twenty unique diet types, where will you fit?

Gene Food uses a proprietary algorithm to divide customers into one of twenty unique diet types based on dietary fat metabolism, ApoE status, carbohydrate response, histamine, and ability to digest lactose. Where will you fit?

West Angeleno

Healthy fats from whole foods, whole grains, fresh over leftovers, and two plant-based days a week.

Low carb, high fat

Wayoan

Plant-based and low-fat. Meat as a condiment, most dairy out, calories from complex carbs, wild fish for protein.

Macrobiotic template

Lean Machine

Whole grains and plant fats, no dairy, protein mostly from plants with wild fish to hold muscle.

Whole grains, plant fats

Villager

Low-fat, whole-food and plant-based. No oil, fresh over aged foods, calories from complex carbohydrates.

Low glycemic, low fat

Okinawan

Fiber-rich complex carbs make up most calories; saturated fat kept low, no seed oils, animal protein as a condiment.

High carb, very low fat

Vegetarian

Plants first with fish in the rotation. Complex carbs for calories, olive oil only, fresh foods to keep histamine down.

High carb, low fat

Urban Grazer

Robust genes, few restrictions. Whole grains, healthy fats, plant proteins, no dairy or processed meat.

Balanced, few limits

Hunter Gatherer

Omega-3s over saturated fat, low-glycemic carbs, mostly plant protein, and fresh foods to keep histamine in check.

Low glycemic, higher protein

Find your diet type

Purchase GeneFood

Find out how your body actually handles carbs

Low-carb works for some people and backfires for others. In the PREDICT-1 trial, genetics accounted for nearly half of the variation in how much blood sugar rose two hours after a meal. Our CLIA-certified test scores your carbohydrate response across multiple validated SNPs, matches you to one of 20 diet types, and turns it into a plan: the carbs that suit you, the ones to limit, and a two-week meal plan built around them.

Frequently asked questions

Variants in the CYP1A2 gene can influence how quickly your body metabolizes caffeine. The same enzymes involved in this pathway also play a role in drug metabolism.

Slow caffeine metabolizers may have a greater risk of heart attack with high caffeine consumption, even in young people. Personalizing caffeine intake to CYP1A2 status can help tailor your caffeine intake to suit your metabolism and improve sleep.

Although CYPA12 is best known for its role in caffeine metabolism, it plays a much larger role in the body. The CYP1A2 gene produces an enzyme that belongs to the cytochrome P450 superfamily.

These cytochrome P450 proteins are monooxygenases, responsible for facilitating various reactions linked to the metabolism of drugs and the synthesis of steroids and cholesterol.

The protein originating from this gene is located in the endoplasmic reticulum and can be activated by certain polycyclic aromatic hydrocarbons (PAHs), some of which are present in cigarette smoke.

While the enzyme’s natural substrate remains unidentified, it can transform certain PAHs into cancer-causing intermediates. Additionally, this enzyme can metabolize various foreign substances, including caffeine, aflatoxin B1, and acetaminophen.

This report is included with the Basic Gene Food DNA test, alongside your diet type and core nutrition reports. Current kit pricing is shown above.

As with all our tests, the caffeine metabolism test is a simple cheek swab test. A self-addressed return envelope is included with the test kit, as are detailed instructions for taking the test. The swab sample is sent to our CLIA-certified laboratory in Houston, where the sequencing occurs. Your raw data file will contain over 700,000 SNPs, one of which will be rs762551, which we use for the caffeine analysis.

View all FAQs