Cannabis Metabolism Genetic Test - Gene Food

Cannabis + Gene Food Diet Type

$424Kit plus Health Intelligence. One-time price.
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Included with Health Intelligence

Cannabis is marketed for health benefits, but is it healthy for you? Learn how your body handles THC and whether you carry genetic markers associated with poor mental outcomes when using cannabis products.

  • CLIA-Certified Lab
  • Personalized DNA insights
  • Data Never Sold

What You'll Learn

  • Tests for important cannabis metabolism genes, including AKT1
  • Data is 100% confidential and secure
  • Personalized nutrition recommendations
  • Learn your Gene Food diet type
Cannabis metabolism report

Learn how your body responds to cannabis

Cannabis is heavily marketed as having health benefits. Less discussed is the risk for those who carry genetic variants associated with poor mental health outcomes when using cannabis products, especially in high doses. The use of products that contain high quantities of Δ9-tetrahydrocannabinol (THC), the main psychoactive ingredient produced by the Cannabis plant, is rapidly increasing in the adolescent population. At the same time, new research tells us that such exposure increases the risk of developing mental health disorders, leading to the onset of depression, and even psychotic symptoms. The Gene Food Cannabis Risk report evaluates several genetic markers associated with poor outcomes when using cannabis products.

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Cannabis metabolism report example
Illustrative report example, not your personal results.
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Find out how your body actually handles carbs

Low-carb works for some people and backfires for others. In the PREDICT-1 trial, genetics accounted for nearly half of the variation in how much blood sugar rose two hours after a meal. Our CLIA-certified test scores your carbohydrate response across multiple validated SNPs, matches you to one of 20 diet types, and turns it into a plan: the carbs that suit you, the ones to limit, and a two-week meal plan built around them.

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Frequently asked questions

Our cannabis polygenic risk score tests for five genes known to impact cannabis metabolism: AKT1, COMT, FAAH, CNR1 (multiple SNPs), DRD2

The way THC is metabolized depends on specific enzymes, which can vary in their activity levels based on genetics.

In states where cannabis is legal, understanding your genetic profile related to cannabis metabolism can help you choose products suitable for your predispositioins, should you decide to use these products. This can include THC/CBD ratios as well as maximum dosing guidelines.

Further, in a teenager, the prefrontal cortex is still maturing and is not fully developed until about age 20-25. This is why using chemicals that constantly stimulate signaling in the brain, like THC, may affect neurological development as the teen grows. Cannabis is not halthy for the teenage brain regardless of genotype, however, some are at greater risk, and that risk can be identified with genetic testing.

Many studies have shown that frequent cannabis use during adolescence can impair cognitive function, increase the risk of mental health disorders, and affect brain structure and connectivity.

It’s still unclear whether genetics plays a role in determining the long-term effects of cannabis on the brain, but it’s possible that individual differences in how the body processes THC could contribute to these effects.

Yes, for example, a study published in the Journal of Neuroscience found that people with a particular SNP of the gene that codes for the enzyme responsible for metabolizing THC, known as FAAH had a stronger response to the drug, including greater feelings of subjective high and increased heart rate. This suggests that genetics plays a role in determining the severity of THC’s effects on the body.

This report is available with the Methylation Bundle (Health Intelligence), alongside the core reports included with your Gene Food DNA test. Current bundle pricing is shown above.

Like all our tests, the Cannabis Risk report is a simple cheek swab test. A self-addressed return envelope is included with the test kit, as are detailed instructions for taking the test. The swab sample is sent to our CLIA-certified laboratory in Houston, where the sequencing occurs.