Ability to Achieve Ketosis & PPARA Gene Test - Gene Food

PPAR-alpha + Gene Food Diet Type

$424Kit plus Health Intelligence. One-time price.
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Included with Health Intelligence

PPAR-alpha activity coded for by the PPARA gene plays an important role in the metabolism of fatty acids and the ability to achieve ketosis. The “G” allele of the SNP rs1800206 (also known as L162V) in the PPARA gene is associated with reduced PPARA activity and increased difficulty entering ketosis.

  • CLIA-Certified Lab
  • Personalized DNA insights
  • Data Never Sold

What You'll Learn

  • Learn whether you carry PPARA gene variants associated with a decreased ability to achieve ketosis and poor saturated fat metabolism
  • Data is 100% confidential and secure
  • Personalized nutrition recommendations
  • Learn your Gene Food diet type
Ability to Achieve Ketosis & PPARA Gene Report

Learn whether you can achieve nutritional ketosis and how your body responds to a high saturated fat diet

Lower PPAR-alpha activity has been associated with an inability to achieve ketosis and an unhealthy metabolic response to diets high in saturated fats—the Gene Food Ability to Achieve Ketosis & PPARA Gene Report evaluates rs1800206 so you can create a personalized approach to dietary fat and ketogenic diets.

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Ability to Achieve Ketosis & PPARA Gene Report example
Illustrative report example, not your personal results.
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Satisfied customers

Amazing
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“Gene Food completely changed the way I approach nutrition. Meal plan is easy to follow, results were ready in 15 minutes, and I no longer crave sweets.”

JL
Jamila Lynn
Hunter Gatherer
The best DNA diet app
★★★★★

“I’ve tried several other companies, including InsiderTracker and DNAfit; if your primary concern is diet then I would absolutely recommend Gene Food as the best of the bunch.”

AP
Alexis Philippou
Urban Grazer
Carbs are GOOD
★★★★★

“Once I went back to carbs (based on the Okinawa diet) and quit the whole 30/paleo diet as well as any attempts at Keto or low-carb, my weight stopped rising, and actually started to go down (and I didn’t even follow the Okinawa diet very strictly, and did no caloric restriction)!”

KC
Kat C.
Okinawan
Best health decision of my adult life
★★★★★

“Acquiring a custom nutrition plan from Gene Food was the single best health decision of my adult life. I frequent the Gene Food blog & the Gene Food podcast. John O’Connor and Dr. Aaron Gardner are focused on providing individuals with the very best science based information today. I believe their individualized approach, not the “one size fits all” seen frequently, is the future of optimizing health and wellness.”

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Bethny Brown-Avila
Wayoan
Diet Types

Twenty unique diet types, where will you fit?

Gene Food uses a proprietary algorithm to divide customers into one of twenty unique diet types based on dietary fat metabolism, ApoE status, carbohydrate response, histamine, and ability to digest lactose. Where will you fit?

West Angeleno

Healthy fats from whole foods, whole grains, fresh over leftovers, and two plant-based days a week.

Low carb, high fat

Wayoan

Plant-based and low-fat. Meat as a condiment, most dairy out, calories from complex carbs, wild fish for protein.

Macrobiotic template

Lean Machine

Whole grains and plant fats, no dairy, protein mostly from plants with wild fish to hold muscle.

Whole grains, plant fats

Villager

Low-fat, whole-food and plant-based. No oil, fresh over aged foods, calories from complex carbohydrates.

Low glycemic, low fat

Okinawan

Fiber-rich complex carbs make up most calories; saturated fat kept low, no seed oils, animal protein as a condiment.

High carb, very low fat

Vegetarian

Plants first with fish in the rotation. Complex carbs for calories, olive oil only, fresh foods to keep histamine down.

High carb, low fat

Urban Grazer

Robust genes, few restrictions. Whole grains, healthy fats, plant proteins, no dairy or processed meat.

Balanced, few limits

Hunter Gatherer

Omega-3s over saturated fat, low-glycemic carbs, mostly plant protein, and fresh foods to keep histamine in check.

Low glycemic, higher protein

Find your diet type
Purchase GeneFood

Find out how your body actually handles carbs

Low-carb works for some people and backfires for others. In the PREDICT-1 trial, genetics accounted for nearly half of the variation in how much blood sugar rose two hours after a meal. Our CLIA-certified test scores your carbohydrate response across multiple validated SNPs, matches you to one of 20 diet types, and turns it into a plan: the carbs that suit you, the ones to limit, and a two-week meal plan built around them.

Gene Food DNA test collection kit

Frequently asked questions

It’s hard to know who to believe in the diet wars. On one hand, you have low-carb advocates saying saturated fat is harmless, while others warn that high-saturated fat diets are dangerous. Knowing your genetic predispositions can help resolve these debates and go beyond theory to find what works best for you.

The “G” allele of the SNP rs1800206 (also known as L162V) in the PPARA gene is associated with reduced PPAR-alpha activity and an increased difficulty of entering ketosis.

A large study found that carriers of the risk G allele benefitted from consuming larger amounts of polyunsaturated fatty acids (PUFA). Carriers of the G allele’s triglyceride and apoC-III levels went up on a low PUFA diet. By contrast, when the PUFA intake increased, they had lower triglyceride and apoC-III levels. The study authors made sure to note that the PUFA response was dose-dependent. The more PUFA G allele carriers ate, the more their triglycerides and apoC-III levels dropped. (R)

By contrast, diets high in saturated fat are contraindicated for carriers of the G allele for rs1800206. Studies show these individuals will have a poor LDL response on high saturated fat diets. (R)

This report is available with the Methylation Bundle (Health Intelligence), alongside the core reports included with your Gene Food DNA test. Current bundle pricing is shown above.

Like all our tests, the Ability to Achieve Ketosis & PPARA Gene Report is a simple cheek swab test. The test kit includes a self-addressed return envelope and detailed instructions for taking it. The swab sample is sent to our CLIA-certified laboratory in Houston, where the sequencing occurs.