COMT/MTHFR Status + Gene Food Diet Type
Learn your status for important COMT SNPs which play a role in dopamine and methylation. The Gene Food COMT Test includes a complete methylation panel as well as a dedicated MTHFR report.
- CLIA-Certified Lab
- Personalized DNA insights
- Data Never Sold
What You'll Learn
- Tests for COMT SNPs, including rs4633 & rs4680
- Includes full methylation panel as well as MTHFR report
- Data is 100% confidential and secure
- Learn your Gene Food diet type and micronutrient needs
Learn your status for important COMT SNPs
The COMT gene encodes an enzyme called called catechol-O-methyltransferase that functions to break down dopamine after its release. This process ensures that just the right dopamine concentration binds to and activates the next neuron. If too much dopamine binds, an increase in impulsive and aggressive behavior is observed. However, if too little binds, depressive/anxious behaviors occur as a result.
COMT variants can therefore be used as molecular genetic markers associated with anxiety, pain, and stress response, however it’s important to note that these variants are common. They cannot be considered defining factors in the development of all mental states, as multiple factors have been shown to play a role.
The COMT variant that determines worrier vs. warrior status is rs4680. The SNP is defined by an amino acid substitution of methionine (Met) in place of valine (Val) at position 158 (Val158Met). Depending on your gene copy number, you could be classed as a worrier (A genotype), a warrior (G genotype), or a mix of the two (AG genotype).

Satisfied customers
Twenty unique diet types, where will you fit?
Gene Food uses a proprietary algorithm to divide customers into one of twenty unique diet types based on dietary fat metabolism, ApoE status, carbohydrate response, histamine, and ability to digest lactose. Where will you fit?
West Angeleno
Healthy fats from whole foods, whole grains, fresh over leftovers, and two plant-based days a week.
Low carb, high fat
Wayoan
Plant-based and low-fat. Meat as a condiment, most dairy out, calories from complex carbs, wild fish for protein.
Macrobiotic template
Lean Machine
Whole grains and plant fats, no dairy, protein mostly from plants with wild fish to hold muscle.
Whole grains, plant fats
Villager
Low-fat, whole-food and plant-based. No oil, fresh over aged foods, calories from complex carbohydrates.
Low glycemic, low fat
Okinawan
Fiber-rich complex carbs make up most calories; saturated fat kept low, no seed oils, animal protein as a condiment.
High carb, very low fat
Vegetarian
Plants first with fish in the rotation. Complex carbs for calories, olive oil only, fresh foods to keep histamine down.
High carb, low fat
Urban Grazer
Robust genes, few restrictions. Whole grains, healthy fats, plant proteins, no dairy or processed meat.
Balanced, few limits
Hunter Gatherer
Omega-3s over saturated fat, low-glycemic carbs, mostly plant protein, and fresh foods to keep histamine in check.
Low glycemic, higher protein
Find out how your body actually handles carbs
Low-carb works for some people and backfires for others. In the PREDICT-1 trial, genetics accounted for nearly half of the variation in how much blood sugar rose two hours after a meal. Our CLIA-certified test scores your carbohydrate response across multiple validated SNPs, matches you to one of 20 diet types, and turns it into a plan: the carbs that suit you, the ones to limit, and a two-week meal plan built around them.







